|
Symbol Name ID |
Pqbp1
polyglutamine binding protein 1 MGI:1859638 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Microcephaly |
Spasticity |
Cerebral atrophy |
Anxiety |
Intellectual disability |
Hyperreflexia |
Global developmental delay |
Seizure |
| Disease(s) Associated with PQBP1 | ||||||||
| Renpenning syndrome |
| Mouse Phenotypes | nervous system phenotype |
decreased brain weight |
decreased brain size |
abnormal hippocampus CA1 region morphology |
abnormal dentate gyrus morphology |
abnormal hippocampus pyramidal cell layer |
thin cerebral cortex |
abnormal neuronal stem cell morphology |
abnormal neuron morphology |
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| Availability | Mouse Genotype | |||||||||
| Pqbp1tm1.1Hiok/Pqbp1+ Tg(Nes-cre)1Kln/0 (conditional) |
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| Pqbp1tm1.1Hiok/Pqbp1+ Tg(Syn1-cre)671Jxm/0 (conditional) |
* | |||||||||
| Pqbp1tm1.1Hiok/Y Tg(Nes-cre)1Kln/0 (conditional) |
* | |||||||||
| Pqbp1tm1.1Hiok/Y Tg(Syn1-cre)671Jxm/0 (conditional) |
* | |||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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